저출력 광조사의 분자 생물학적 기전
Molecular Biologic Mechanism of Low Level Light Therapy
임원봉, 최홍란, 김병국, 김지선, 김옥준,
소속 상세정보
임원봉 ( Lim Won-Bong ) - 전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소
최홍란 ( Choi Hong-Ran ) - 전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소
김병국 ( Kim Byung-Gook ) - 전남대학교 치의학전문대학원 구강내과 및 치의학연구소
김지선 ( Kim Ji-Sun ) - 전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소
김옥준 ( Kim Ok-Joon ) - 전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소
KMID : 0829220120360010031
Abstract
Low level light therapy (LLLT) is known to accelerate the process of wound healing, bone and cartilage formation, and to decrease tissue necrosis and inflammation. It also can be applicable to acute and chronic injury or degenerative disease. Despite forty-plus years of accumulating exprerience of the clinical efficacy of LLLT, their molecular biologic evidence is not fully elucidated. The aim of this review is to explore the role of the ROS system and its molecular biologic mechanism in related with inflammatory response, anti-apoptosis and angiogenesis during LLLT. We suggest that activation of ROS system explains many (if not most) of the observed response of cells to LLLT in vitro, and is likely to play a pivotal role in the response of animals and patients to LLLT for both experimental and clinical indications and diseases.
키워드
Low level light therapy; Reactive oxygen species
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